Methadone Side Effects part 3
This medication Methadone may be prescribed for other uses; ask your doctor or pharmacist for more information about other uses..
Are there any special precautions you should follow before taking my methadone prescription?
Full disclosure of any and all medical/health problems are important for any medication being prescribed. It is your responsibility to inform the doctor of any health problems you are having or may have recently had
1. You should tell your doctor if you are allergic to methadone or any other medications.
2. You should tell your doctor about any prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take.
3. You should tell your doctor what herbal products you are taking, especially St. John’s Wort.
4. You should tell your doctor if you have or have ever had asthma or other breathing problems or a blockage in your intestine. Your doctor may tell you that you should not take methadone.
5. You should tell your doctor if you have or have ever had a head injury, a brain tumor, a stroke, or any other condition that caused high pressure inside your skull; irregular heartbeat; urethral stricture (narrowing of the tube that carries urine out of the body), enlarged prostate (a male reproductive gland), or any other condition that causes difficulty urinating; Addison’s disease (a condition in which the body does not make enough of certain natural substances); mental illness; chronic obstructive pulmonary disease (COPD; a group of lung diseases); kyphoscoliosis (condition in which the spine curves abnormally); sleep apnea (condition in which breathing stops for short periods during sleep); low levels of potassium or magnesium in your blood; or thyroid, heart, liver, or kidney disease. Also, tell your doctor if you drink or have ever drunk large amounts of alcohol or if you use or have ever used street drugs or have overused prescription medications. You should tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking methadone, call your doctor. There should be no problems if you follow the guidelines presented to you.
6. If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking methadone.
7. You need to be aware that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. You need to know that alcohol can add to the drowsiness that may be caused by this medication. You should tell your doctor if you use tobacco products. Smoking may be problematic for you.
8. You should be aware that one of the side effects of methadone may cause dizziness when you get up too quickly from a prone position. This is more common when you first start taking methadone. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
Interactions are possible:
Any of the following may cause negative interactions: antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Ave nty I, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); certain antifungals such as fluconazole (Oiflucan), itraconazole (Sporanox), ketoconazole (Nizoral), and voriconazole (Vfend); antihistamines; buprenorphine (Subutex); butorphanol (Stadol NS); calcium channel blocking agents such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (OynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine (Sular), and verapamil (Calan, Covera, Isoptin, Verelan); diuretics (‘water pills’); erythromycin (E.E.S., E-Mycin, Erythrocin); laxatives; medications for anxiety, mental illness, nausea, or pain; medications for HIV including abacavir (Ziagen), amprenavir (Agenerase), didanosine (Videx), efavirenz (Sustiva), lopinavir (in Kaletra), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra), stavudine (Zerit), and zidovudine (Retrovir); certain medications for irregular heartbeat such as disopyramide (Norpace), f1ecainide (Tambocor), mexiletine (Mexitil), moricizine (Ethmozine), procainamide (Procanbid, Pronestyl), propafenone (Rythmol), propranolol (Inderal), quinidine (Quinidex), and tocainide (Tonocard); certain medications for seizures such as carbamazepine (Carbatrol, Epitol, Tegretol), phenytoin (Dilantin, Phenytek); phenobarbital nalbuphine (Nubain); naloxone (Narcan);naltrexone (ReVia, Depade); pentazocine (Talwin); rifampin (Rifadin, Rimactane, in Rifamate); risperidone (Risperdal); sedatives; certain selective serotonin reuptake inhibitors (SSRls) such as fluvoxamine (Luvox) and sertraline (Zoloft); sleeping pills; certain steroids such as cortisone, fludrocortisones (Flurinef), and hydrocortisone (Cortef); and tranquilizers. Also, you should tell your doctor if you are taking the following medications or have stopped taking them in the past 14 days: monoamine oxidase (MAO) inhibitors including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelpar), and tranylcypromine (Parnate). Many other medications may also interact with methadone, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
Are there any special dietary instructions should I need to know?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine. You should not eat or drink either.
What should I do if I forget or miss a dose?
If your doctor has told you to take methadone regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throwaway any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. You should store methadone in a safe place so that no one else can take it accidentally or on purpose. Keep track of how many tablets or how much solution or concentrated solution is left so you will know if any is missing.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include:
• Small, pinpoint pupils (black circles in the center of the eyes)
• Slow or shallow breathing
• Cool, clammy, or blue skin
• Loss of consciousness; coma
• Limp muscles
What other information should I know?
You should keep all appointments with your doctor, laboratory, and clinic staff. Your doctor will want to check your response to methadone. It is important for you to keep a written list of all of the prescription and non-prescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. You should also try make yourself as knowledgeable as possible about everything you taking. You should not be afraid to ask questions.